Viagra and Cialis are part of a family of medications called PDE-5 inhibitors. Viagra and Cialis work by blocking PDE This maintains elevated levels of a substance known as cGMP, which relaxes smooth muscle and encourages blood vessels to widen. That makes blood flow more freely, including to the penis.
Viagra and Cialis can be effective in as little as 1 hour, though for some patients, these medicines can work more rapidly. Viagra leaves the body in about 6 to 8 hours, while Cialis can work for 24 to 36 hours.
Nevertheless, the effect of a medication may not be needed beyond 6 or 8 hours, and any side effects in addition to any positive effect they cause will fade rapidly as the medication leaves the bloodstream. That means that someone who experiences nasal congestion or flushing when they use either Cialis or Viagra may find it useful to take the shorter acting medication, Viagra. The length of time a medicine works is important to some. One might be able to predict when sexual activity will occur.
A drug that works rapidly and leaves his system quickly thereafter would be perfect, as with Viagra. Another man might know sex will occur during the course of a weekend but cannot know exactly when that will occur. For him, a drug with a prolonged period of activity is far more important than how long it takes for a medicine to start working.
He would prefer Cialis. Also, Cialis can be taken in a low daily dose, and for a solid subset of patients, this is preferred. Common side effects of Viagra and Cialis include dizziness, headache, flushing, upset stomach or indigestion, blurred vision, changes in vision color, flu-like symptoms such as a runny or stuffy nose or sore throat , memory problems, muscle or back pain, insomnia, or abnormal ejaculation. The side effects you experience might determine whether Viagra or Cialis is the right choice for you.
Erections are caused by the engorgement of the penis with blood. Under regular conditions, sexual stimulation and arousal leads to the production and release of nitric oxide in the penis. Nitric oxide is responsible for the activation of the enzyme guanylate cyclase, which causes the production of cyclic guanosine monophosphate cGMP. It is this cGMP that is primarily responsible for the erection as it affects the amount of blood that the blood vessels will deliver and remove from the penis.
Tadalafil and sildenafil inhibit PDE5. By preventing the destruction of the cGMP and allowing it to accumulate and persist for longer in the penis, the penis can remain engorged, firm, and long for longer. Think of PDE5 inhibitors like the brakes on the car. Removing the brakes allows the car to go faster and further more easily. Viagra sildenafil is a few years older than Cialis tadalafil and was the first oral treatment for erectile dysfunction approved by the FDA. On March 27th, , Viagra sildenafil became the first oral pill, and first PDE5 inhibitor, to be approved by the Food and Drug Administration to treat erectile dysfunction in the U.
Viagra sildenafil was developed and sold exclusively by the pharmaceutical company Pfizer for 15 years until their patents expired in and the first generic versions were introduced. After this, other companies were legally allowed to produce, market, and sell their own version of sildenafil. The first generic sildenafil was approved in March of and released on the market in December of Cialis was first approved for treating erectile dysfunction on November 21st, and was the third PDE5 inhibitor to hit the market after vardenafil [Levitra].
The pharmaceutical company named Eli Lilly was the developer and patent-holder for tadalafil until November of After key patents expired, several other companies were permitted to make their own versions of tadalafil and sell these cheaper options on the market.
Cialis tadalafil will stay in your body for four to six times longer than Viagra sildenafil. Both Viagra sildenafil and Cialis tadalafil can reach their maximum effectiveness in as little as an hour, but for some patients they may work more quickly. One of the largest differences between the two medications is how long they stay in your body. Viagra sildenafil will stay in your body for six to eight hours but Cialis tadalafil can work for an incredible 24 to 36 hours.
For this reason, Cialis is often known as "the weekend pill. If you experience any side effects while taking erectile dysfunction medications, it may be a better choice to go for the one with the shorter duration. Cialis tadalafil can be prescribed for daily use with doses of 2. Since Cialis tadalafil will stay in your body longer, it changes the options for the prescription a little when compared to Viagra sildenafil.
For example, Cialis can either be taken as a daily dose or only when needed. They often help address the issue. The medications work in similar ways. However, they also have some key differences, such as when you take them, how long they work, and what their side effects are. Viagra, Cialis, Levitra, and Stendra are all in a class of medications called phosphodiesterase type 5 PDE5 inhibitors.
These drugs work by blocking the PDE5 enzyme. They also boost a chemical in your body called nitric oxide. This action encourages the muscles in your penis to relax. It also helps you maintain the erection long enough to have sex. Both Viagra and Cialis can be taken 30 minutes before sexual activity. However, Cialis lasts much longer and is noteworthy for the amount of time it remains in your body. You may feel the effects of the drug up to 36 hours after you take it.
The fact that it comes in a low dose of 2. This side effect is not associated with any other oral ED drugs. Viagra can take 30 to 60 minutes to work in the body, while Levitra takes 60 minutes. The effects of both drugs last for about 4 hours. Vision color changes are considered side effects of both Viagra and Levitra. Stendra is the newest drug on the market. No generic version is available for sale yet. A hallmark of Stendra is its fast-acting nature.
You can take the mg and mg doses as shortly as 15 minutes before sexual activity. As a second-generation medication, Stendra also seems to have milder side effects than Viagra and the other PDE5 inhibitors that came before it. Side effects commonly caused by Viagra — but not Stendra — include vision changes, nausea, and muscle aches. The only common side effect caused by Stendra — but not Viagra — is a sore throat. As mentioned earlier, Cialis can be used as a daily medication to treat enlarged prostate, unlike Levitra, which is strictly used as a treatment for erectile dysfunction.
Cialis is also faster acting than Levitra. You can take it 30 minutes before sexual activity, while you should take Levitra at least 1 hour in advance. Cialis and Levitra both have similar side effects, but some side effects unique to Cialis include muscle aches and pain in the limbs.
These medications are available in a variety of doses, ranging from 2. You can take all of them with or without food. However, taking Viagra, Levitra, or Stendra after eating a high fat meal does slow the rate of absorption.
Most of them stay in your bloodstream for about 4 to 5 hours. Cialis is the exception, as it remains in your bloodstream for up to 36 hours. Tell your doctor if you have any side effects that linger and do not go away on their own. You can get a prescription through your doctor or online through telehealth companies. If you have health insurance, keep in mind that most insurance companies will not cover the cost of your prescription.
However, if you have certain medical conditions, your health plan may pay for the drug with prior authorization. The exact price you pay for any drug will depend on your insurance plan, if you have one, and your pharmacy. Generic versions of Viagra, Cialis, and Levitra can cost half as much as their brand-name counterparts, if not less.
Make sure to talk with your doctor or a healthcare professional before purchasing any ED medications, especially if you are buying them online.
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